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Cenforce 200 mg, which contains sildenafil citrate, is primarily used to treat erectile dysfunction (ED). As with any medication, it can interact with other drugs, potentially leading to adverse effects or reduced efficacy. Here are some key interactions:

Nitrates: Cenforce 200 Mg can cause a significant drop in blood pressure when taken with nitrates, commonly prescribed for chest pain (angina). This combination can be dangerous and is contraindicated.

Alpha-blockers: Medications used for hypertension and benign prostatic hyperplasia (BPH) like doxazosin, tamsulosin, and others can interact with sildenafil, leading to a significant drop in blood pressure, causing dizziness or fainting.

Antihypertensives: Sildenafil can enhance the blood pressure-lowering effect of antihypertensive drugs. This includes various types of blood pressure medications such as diuretics, ACE inhibitors, beta-blockers, and calcium channel blockers.

CYP3A4 inhibitors: Drugs that inhibit the CYP3A4 enzyme, such as ketoconazole, itraconazole, erythromycin, and protease inhibitors (used in HIV therapy), can increase sildenafil levels in the blood, potentially increasing side effects.

CYP3A4 inducers: Drugs that induce CYP3A4, such as rifampin and certain antiepileptic drugs (like carbamazepine and phenytoin), can decrease the effectiveness of sildenafil by reducing its concentration in the blood.

Other ED medications: Combining sildenafil with other ED medications like tadalafil (Cialis) or vardenafil (Levitra) can increase the risk of adverse effects and is generally not recommended.

Grapefruit juice: Grapefruit juice can inhibit the metabolism of sildenafil, leading to increased levels in the blood and a higher risk of side effects.

Alcohol: While not a direct drug interaction, alcohol can exacerbate the blood pressure-lowering effects of sildenafil and increase the likelihood of side effects such as dizziness or headache.

It's crucial to inform your healthcare provider about all medications you are currently taking, including over-the-counter drugs, supplements, and herbal products, to avoid potential interactions and ensure the safe use of Cenforce 200 mg.