No, Cenforce Soft (which contains sildenafil, the active ingredient in Viagra) should not be taken with nitrates. Nitrates are commonly prescribed for heart conditions, such as angina, to help relax blood vessels and improve blood flow. Both Cenforce Soft and nitrates work by increasing nitric oxide levels, which dilate blood vessels. When taken together, they can cause a dangerous drop in blood pressure, leading to dizziness, fainting, heart attack, or stroke. It's essential to consult a healthcare provider before combining any medications, particularly if you're using nitrates, to ensure safety and avoid serious interactions.