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Fildena 120 mg is a medication that contains sildenafil, the active ingredient commonly used to treat erectile dysfunction (ED). The reason it has a long duration of action is due to how sildenafil works in the body. Here are the key factors:

Mechanism of Action: Fildena 120 mg works by inhibiting the enzyme phosphodiesterase type 5 (PDE5) in the smooth muscle cells of the penis. PDE5 normally breaks down cyclic GMP, a molecule that helps relax blood vessels in the penis, allowing for increased blood flow during sexual arousal. By inhibiting PDE5, sildenafil helps maintain high levels of cyclic GMP, promoting prolonged blood flow and improving erectile function.

Half-Life: The half-life of sildenafil (the time it takes for half of the drug to be eliminated from the body) is around 4 hours. This means that the effects of Fildena can last for several hours, though the peak effect is typically observed within 1-2 hours of ingestion. It may stay in your system longer, providing a window of action over a 4 to 6-hour period.