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If you're taking Tadalista occasionally for erectile dysfunction (ED), missing a dose isn't usually a problem. It's meant to be taken before planned sexual activity, not on a strict daily schedule, so there’s no need to "make up" for a missed dose. Never take two doses at once to make up for a missed one. Doubling up can increase the risk of side effects such as low blood pressure, dizziness, or priapism (a prolonged erection), which can be dangerous. If you're uncertain about what to do after missing a dose—or whether you should be on a daily or as-needed regimen—speak with your healthcare provider. They can provide personalized guidance based on your condition and treatment plan.