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Roberttanser · 12-04-2024 12:48:34

Cenforce 100 mg, like other medications for erectile dysfunction (ED) containing sildenafil citrate, requires sexual stimulation to work because of the way it affects the physiological processes involved in achieving an erection.

Here's how it works:

Pharmacological Action: Cenforce 100 belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. When a man is sexually stimulated, nitric oxide is released in the erectile tissue of the penis. Nitric oxide activates an enzyme called guanylate cyclase, which increases levels of cyclic guanosine monophosphate (cGMP).

Relaxation of Smooth Muscle: Increased levels of cGMP cause the smooth muscles in the walls of the blood vessels in the penis to relax. This relaxation allows blood to flow more freely into the erectile tissue, leading to an erection.

Role of PDE5: However, the action of cGMP is normally limited by another enzyme called phosphodiesterase type 5 (PDE5), which breaks down cGMP. By inhibiting the action of PDE5, medications like Cenforce 100 mg help to maintain higher levels of cGMP in the penis, prolonging the relaxation of smooth muscle and enhancing blood flow, resulting in an erection.

So, while Cenforce 100 mg can facilitate the physiological processes involved in achieving an erection, it does not directly cause an erection on its own. Sexual stimulation is still necessary to initiate the release of nitric oxide and activate the cascade of events that lead to an erection. Cenforce 100 mg simply enhances the body's response to sexual stimulation, making it easier for a man to achieve and maintain an erection when aroused.

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wolfeh · 04-06-2024 04:25:42

wolfeh · 19-08-2024 11:03:04

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Forum

#1 12-04-2024 12:48:34

Why does Cenforce 100 Mg require sexual stimulation to work?

#2 05-05-2024 05:26:16

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#3 05-05-2024 05:27:31

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#4 04-06-2024 04:24:27

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#5 04-06-2024 04:25:42

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#6 19-08-2024 11:03:04

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#7 19-08-2024 11:04:20

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#8 20-08-2024 12:44:55

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#9 28-09-2024 12:27:01

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#10 19-10-2024 01:28:50

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#11 28-10-2024 17:33:31

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#12 17-06-2025 09:35:06

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#13 22-06-2025 13:33:46

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#14 26-06-2025 16:07:43

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#15 27-06-2025 15:29:38

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#16 04-07-2025 14:01:39

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#17 05-07-2025 18:20:55

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#18 18-07-2025 14:42:45

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#19 19-07-2025 12:10:47

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#20 21-07-2025 13:50:25

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#21 22-07-2025 15:11:44

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#22 23-07-2025 11:22:00

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#23 26-07-2025 12:18:58

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#24 27-07-2025 12:37:55

Re: Why does Cenforce 100 Mg require sexual stimulation to work?

#25 29-07-2025 13:57:02

Re: Why does Cenforce 100 Mg require sexual stimulation to work?