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However, the majority of the studies on conjugated linoleic acid leading to weight loss have been carried out on animals. According to a review of research, weight loss appears to be minimal in human studies. According to the National Institute of Health’s Office of Dietary Supplements, pyruvate may have some effects on weight loss. A 2005 study of 176 people indicated that glucomannan contributed to weight loss in healthy, overweight adults. It is important to research carefully before choosing a weight loss pill, as some may have side effects, or interact with existing conditions.

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