Tadalista 10 mg (tadalafil) — like other tadalafil‑based PDE5 inhibitors — does not directly affect blood cholesterol levels in most people. There’s no strong evidence that it raises total cholesterol, LDL (“bad†) cholesterol, or alters lipid metabolism on its own.  What Research Shows 1. No direct effect on cholesterol: Tadalafil isn’t linked to changes in total cholesterol, LDL, HDL, or triglyceride levels in clinical studies comparing it with placebo. Variables like lipid levels stayed essentially the same with tadalafil treatment. High cholesterol is not listed as a known side effect in official prescribing information for tadalafil, and clinical evidence does not support a causal link between tadalafil use and elevated cholesterol. 2. Shared cardiovascular conditions: Erectile dysfunction and high cholesterol commonly occur Tadalista 10 mg because both are tied to cardiovascular disease risk factors (such as diabetes, obesity, metabolic syndrome), not because tadalafil directly causes cholesterol issues. 3. Preliminary exploratory findings: Some small, preliminary research in healthy volunteers suggested tadalafil might lower the ApoB/ApoA‑1 ratio (a cardiovascular risk marker) without changing LDL or HDL levels, but this is not definitive evidence of cholesterol reduction and needs more research. What This Means for You Tadalista 10 mg is unlikely to change your cholesterol levels directly. If your cholesterol goes up or down while taking it, that change is most likely due to diet, lifestyle, underlying health conditions, or other medications — not the tadalafil itself. High cholesterol and ED often coexist because of shared cardiovascular risk factors. Managing cholesterol with diet, exercise, and medications like statins is still important for overall heart health and can also help erectile function indirectly.
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