Fildena is a brand of sildenafil, which is commonly used to treat erectile dysfunction. Its interaction with meals, especially high-fat meals, is important for its effectiveness. Here’s a detailed explanation: Absorption Delay: Sildenafil is absorbed in the small intestine. High-fat meals slow down gastric emptying, which delays the drug reaching the intestine. Effect on Onset of Action: Fildena, sildenafil works within 30–60 minutes on an empty stomach. After a high-fat meal, it can take up to 2 hours to start working. Effect on Overall Effectiveness: The maximum blood concentration (Cmax) might be slightly lower with a high-fat meal. However, the overall effectiveness (duration and magnitude) is generally not significantly reduced; it just takes longer to start. Practical advice: For faster onset, take Fildena on an empty stomach or with a light meal. Avoid heavy, greasy meals right before taking it if you want it to work quickly. If you want, I can make a tiny table showing exactly how food types affect Fildena absorption and onset—it’s very easy to reference.